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ylxR [2019-05-24 08:50:03]
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ylxR [2019-05-24 08:50:03]

nucleoid-associated protein
locus
BSU16610
pI
10.09
mw
10.27 kDa
protein length
91 aa Sequence Blast
gene length
276 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
ymxB
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.7|Proteins of unknown function]

    • Gene

    Coordinates
    1,733,410 → 1,733,685

    The protein

    Structure

  • [PDB|1G2R] (from ''Streptococcus pneumoniae'', 47% identity) [Pubmed|11679764]

    • Expression and Regulation

    Operons

    genes
    [gene|9F6C447900410BF64409E5C41A11C76968DADAFA|ylxS]-[gene|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|nusA]-[gene|F4097349A563503468A2A14F062AEAC532C7917A|ylxR]-[gene|7BFA65857F69855DBB3BB64D93B4ED2F09DC705B|rplGA]-[gene|378B77412D0DEA220A97DEC246410509D9B74D46|infB]-[gene|24835CE6CD2E1F183DB9121F29A63101718B5DF9|ylxP]-[gene|B3119A40393A288EF34FC3E9839B6E40AC6A6EA0|rbfA]
    description
    [Pubmed|8491709]

    sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|8491709], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]
  • [protein|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB]: sigma factor, [Pubmed|15805528,26577401], in [regulon|580011DE5DC40EC9E7E0512791D328FAA010DCB8|SigB regulon]

    • regulatory mechanism

  • [regulon|stringent response|stringent response]: negative regulation, in [regulon|stringent response|stringent response]
  • [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA]: attenuation, [protein|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA] stimulates termination [Reference|http://www.nature.com/articles/nmicrobiol20157], in [regulon|8887ADC77C43F21CD375BDAA4D38E940786DAD4F|NusA regulon]

    • regulation

  • autoregulation [SW|NusA] [http://www.nature.com/articles/nmicrobiol20157 reference]
  • induced by glucose [pubmed|30355672]
    • view in new tab

    Biological materials

    Mutant

  • MGNA-B078 (ylxR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1077 NBRP B. subtilis, Japan]
  • BKE16610 (Δ[gene|F4097349A563503468A2A14F062AEAC532C7917A|ylxR]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE16610 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCTAAAGTCACCTCTTAT, downstream forward: _UP4_CTGGCGGAAAAGGTGAAAAA
  • BKK16610 (Δ[gene|F4097349A563503468A2A14F062AEAC532C7917A|ylxR]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK16610 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CACCTAAAGTCACCTCTTAT, downstream forward: _UP4_CTGGCGGAAAAGGTGAAAAA

    • References

  • 11948165,8491709,11679764,30355672